Cost of atorvastatin 20 mg /day and 50 mg/day, respectively, compared with niacin 300 mg/day, were greater in the Pravastatin (P <.01) and DPP-40000 arms (Table 2).
Table 2. Treatment Groups Patients With T1D T2D Mean +/- SD with P <.05 Mean (n = 842) 2434) Age, yr 60.4 ± 10.9 66.4 13.4 (mean SD) 60.9 ± 9.6 Sex Distribution Female 43.5% 40.7% Male 57.6% 39.2% Race/Ethnicity Non-Hispanic White, non-Hispanics 50.1% 50.0%% Black, 51.0% 48.5%% Mexican, non-Hispanic 12.4% 13.2% Japanese, non-Hispanics 2.6% 3.1% Indian, non-Hispanic 1.3% 1.5% Marital Status Married 63.5% 57.3% Widowed 11.3% Divorced 36.5% 34.4% Live with children 25.1% 21.9% Living cost of atorvastatin uk alone 21.2% 16.2% Education, y 12.0 ± 4.2 13.9 4.7 12.5 3.9 Body Mass Index, kg/m2 27.5 ± 3.9 27.1 3.7 27.0 3.3 Body Fat % 26.5% 25.1% 27.7% BMI, kg/m2 28.3 ± 4.2 28.2 4.1 27.9 2.9 Fasting glucose level, mg/dL 130 ± 17 2-h OGTT, mg/dL 97 ± 53 95 47 96 54 HbA1c, % 11.1% 14.3% 10.0% Mean CRP level, mg/L 9.9 ± 3.8 9.7 4.0 (mean SD) 9.5 ± 2.8 HDL cholesterol, mmol/L 1.17 ± 0.35 1.18 0.34 Blood pressure, mm Hg 118.7 ± 10.2 120.7 10.6 Open in a separate window
The Pravastatin arm had a significantly greater reduction in HbA1c levels (15.5% ± atorvastatin nombre generico 3.1%) than did the DPP-40000 arm (8.5% ± 1.7%). In contrast, the Pravastatin arm had a significantly greater reduction in the HOMA-IR index (1.35 ± 0.24) than did the DPP-40000 arm (0.66 ± 0.11), although both doses significantly reduced the mean blood pressure compared to placebo (Table ).
Adverse Events, Discontinuations, and Recipients of Pravastatin. HbA1c concentrations at week 12 in the Pravastatin arm and at week 12 in the DPP-40000 arm were not significantly different.
After 1 year, 52% of patients had discontinued study medication. At 1 year, the mean duration of therapy with Pravastatin was 3.0 months, and the mean dose was 25 mg/day. In contrast, Pravastatin had an early discontinuation rate of 18% (p <.01).
In the first year, 48% of patients reported at least one adverse event.
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Atorvastatin is used to treat high cholesterol. Atorvastatin is also used to lower the risk of stroke, heart attack, or other heart complications in people with coronary heart disease or type 2 diabetes. Atorvastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body. Atorvastatin reduces low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood. Lowering your cholesterol can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease.
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Cost of atorvastatin uk. The authors state, "The differences in the cost of atorvastatin (Atenolol) between the U.K. and Europe is not trivial," although they do note that the net cost of U.K.-only versus EU-only prescribing in the U.K. would likely be lower. The authors highlight following online pharmacy auckland nz important insights: Atorvastatin U.K. would have atorvastatin generics pharmacy price an overall lower cost of prescribing than atorvastatin EU. The U.K.'s differential cost of prescribing could be explained by the fact that U.K. uses different generic manufacturing processes and an increased number of countries/regions, thus making it more costly to manufacture in the U.K. (for example, China produces atorvastatin in large quantities). EU.K. will have lower gross margins in the longer run, however. European Union prescribers consume 40% less atorvastatin. This could mean lower prescriptions for both the U.K. and EU. Atorvastatin EU.K. is more expensive per mg of atorvastatin (about €9 in the U.K., and €10 EU - 0.48% for atorvastatin the generics pharmacy EMEA). The authors argue that this is mainly due to the risk of heart failure. In summary, we argue that differences in the cost of atorvastatin Europe, are likely to explain the differential access and use of atorvastatin in EU alone. the long run this difference could explain the greater average annual prescription bill for atorvastatin U.K. For more info about how we did this article, read an additional section "How Did Our Readers Interpret Findings?" How Did Our Readers Interpret Findings? Although the article itself did not provide any clear interpretation, we received many comments from readers regarding the findings, which can be read below: Our readers didn't agree with conclusion that atorvastatin EU would have a lower net cost than atorvastatin U.K. (on average, the EU vs alone would cost atorvastatin uk. €21,742 as opposed to €35,091 for atorvastatin EU. This would suggest that the U.K. might obtain more atorvastatin from other sources). Our readers also didn't agree with our conclusion that the differential cost of prescribing for the EU vs alone U.K. could be explained Buy benzamycin gel online by the fact that there is greater access to atorvastatin from other EU countries, thus lowering its net cost. Our readers didn't agree with conclusion that Atenolol (Actemra) would cost at least half as much in the U.K. it would Europe (€15,935 for atorvastatin U.K., as opposed to €19,000 for atorvastatin EU. Europe the drug costs about €16,908, compared to €18,000 for Atorvastatin U.K.). Our readers weren't convinced that the differences in pricing could be explained by increased drug production costs. Our readers didn't agree with conclusion that the differential cost of prescribing for the U.K. could be explained by the increased demand on Atorvastatin EC, which would drive up Atorvastatin EC prices. Our readers found conclusion that the differential between prescribing Atenolol (Lamictal) and (EudraCT) in Europe would not be explained by differences in the volume of prescription at which the drugs were dispensed.
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